Personally, I grew up on the internet, learning from people in chatrooms and forums which were strong communities where most of my personal adult relationships have come from (many of whom I've not met in 20 years of knowing them).

From what I've seen, if your seniors and your juniors are both from this era and culture, your remote team will excel without missing a beat. I think it's the people used to the "old ways" that will suffer, for having expensive requirements like an office to capture the same value.

You have moved the goalposts from "not hospitalized" to "asymptomatic or very minor symptoms". About half the people I know who got covid (and knew about it) had, or are currently having, a very unpleasant time.