There’s a hopefully unrelated concept called purple urine bag syndrome I have seen. Not completely understood either but this paper thinks due to a combination of dietary tryptophan breakdown from constipation and colonic E coli load, urinary bacteria, and reaction with the plastic tubing of the catheter and bag.
Not directly since we all have it. It’s a bit confusing from the article but basically they discovered an antibiotic which can target a narrower spectrum than before which will minimize messing up your natural flora and allow drug resistant enterobacter (e coli is a main species, but not the only one) to be over represented. There is an association with ibd and. microbiomes that have e coli over-represented. And there are some subtypes of e coli that appear to be associated, see:
I didn’t see any mention in the article about the rise of obesity as a possible cause.
Aside from the social aspects which could be debated, older obese adult men are more likely to have medical conditions that would decrease their ability to have sex.
I think the other reasons they posted are valid but was expecting a comment on that.
Ahh I bet that is where the confusion is. I am a physician and I have used methylene blue in severe shock and methemoglobinemia but I was a bit worried the parent comment believed it’s a valid CO treatment.