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It works on people with e specific birth gene defect named OTOH. So likely not helping with tinnitus.

> So likely not helping with tinnitus.

Not directly, no, but here's hoping that it leads to something in the adjacent field of Tinnitus.


From what I've seen recently tinnitus research is moving into completely different direction as it seems related to sleep.

Calibra might help to put some benchmark numbers on your prototypes: https://calibra.swival.dev/

Great news! Expecting this to get implemented in all the major inference runners pretty fast. See also: https://news.ycombinator.com/item?id=47637422


User @thin_signal developed a tool for mixed precision quantization on MLX. They perfoemd a sensitivity analysis across the model layers and applied less radical quantization on the layers more sensitive and more quantization tomlayers that are more robust.

The tool, which is documented here (https://mlx-optiq.pages.dev/) also implements the recently aanounced TurboQuant KV-Cache optimization, so in total this should greatly improve the quality of locally run LLMs.

Looking forward to an OptiQ release of the Gemma 4 family.


This is so annoying.

Along the same line is that you can watch any hour long video without interruptions unless it is music where you will get interrupted every couple of minutes with "are you there?" dialogues.



Why not Quarto? Genuinely curious.


I already use MkDocs, I don't use NodeJs. I looked for something in the Python ecosystem, but everything is JS. So i wanted to see if I could create it myself :)


The Tick live action series with Patrick Warburton is unmatched. Too bad it got cancelled after nine episodes. But those are pure gold.


Maybe teach zhem how to cook? Much cheaper.


Wondering if it were feasible to vibe-code a Bot that would engage and invest the little sums that yield those bait gains, and harvest those. Eject at the right time.


Great original idea, you should make a Beowulf Cluster of them! With a Java Applet!


This made me taste cringe. It’s orange flavoured and weirdly acidic like something the dentist used on me when I was 7.


Wondering why they are not using uv instead of pip in the container, give that uv is much faster than pip.


You can tell it to install uv. I just ran this:

  Run "pip install uv" then run
  "uv tool install sqlite-utils"
  then "sqlite-utils --version"
And it worked: https://claude.ai/share/df36f3a8-44f0-4c7d-bb64-e5ed57602d79

I imagine they still default to pip because there's more training data about it, and it works fine.


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