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1.
Founder of GitLab battles cancer by founding companies (sytse.com)
1404 points by bob_theslob646 76 days ago | 255 comments
2.
Drug trio found to block tumour resistance in pancreatic cancer in mouse models (drugtargetreview.com)
271 points by axiomdata316 4 months ago | 150 comments
3.
Fabrice Bellard Releases MicroQuickJS (github.com/bellard)
1507 points by Aissen 5 months ago | 569 comments
4.
Useful patterns for building HTML tools (simonwillison.net)
354 points by simonw 6 months ago | 93 comments
5.
macOS 26.2 enables fast AI clusters with RDMA over Thunderbolt (developer.apple.com)
540 points by guiand 6 months ago | 291 comments
6.
OpenAI are quietly adopting skills, now available in ChatGPT and Codex CLI (simonwillison.net)
587 points by simonw 6 months ago | 324 comments
7.
UniFi 5G (ui.com)
373 points by janandonly 6 months ago | 309 comments
8.
Agent design is still hard (pocoo.org)
426 points by the_mitsuhiko 6 months ago | 258 comments
9.
Phone numbers for use in TV shows, films and creative works (acma.gov.au)
287 points by nomilk 7 months ago | 139 comments
10.
Kimi Linear: An Expressive, Efficient Attention Architecture (github.com/moonshotai)
217 points by blackcat201 7 months ago | 47 comments
11.
Computer science courses that don't exist, but should (2015) (dadgum.com)
367 points by wonger_ 7 months ago | 299 comments
12.
The death of thread per core (buttondown.com/jaffray)
155 points by ibobev 7 months ago | 68 comments
13.
Getting DeepSeek-OCR working on an Nvidia Spark via brute force with Claude Code (simonwillison.net)
201 points by simonw 7 months ago | 45 comments
14.
Our modular, high-performance Merkle Tree library for Rust (github.com/bilinearlabs)
144 points by bibiver 7 months ago | 29 comments
15.
Show HN: Recall: Give Claude memory with Redis-backed persistent context (npmjs.com)
171 points by elfenleid 8 months ago | 93 comments
16.
Where it's at:// (overreacted.io)
416 points by steveklabnik 8 months ago | 255 comments
17.
FLX1s phone is launched (furilabs.com)
337 points by slau 8 months ago | 262 comments
18.
486Tang – 486 on a credit-card-sized FPGA board (nand2mario.github.io)
196 points by bitbrewer 9 months ago | 57 comments
19.
Show HN: Building a Deep Research Agent Using MCP-Agent (thealliance.ai)
91 points by saqadri 9 months ago | 20 comments
20.
VaultGemma: The most capable differentially private LLM (research.google)
125 points by meetpateltech 9 months ago | 22 comments
21.
Show HN: I'm a dermatologist and I vibe coded a skin cancer learning app (molecheck.info)
429 points by sungam 9 months ago | 259 comments
22.
Show HN: Semantic grep with local embeddings (github.com/beaconbay)
179 points by Runonthespot 9 months ago | 78 comments
23.
OpenSSH Post-Quantum Cryptography (openssh.com)
446 points by throw0101d 10 months ago | 127 comments
24.
Why LLMs Can't Write Q/Kdb+: Writing Code Right-to-Left (medium.com/gabiteodoru)
195 points by gabiteodoru 11 months ago | 145 comments
25.
Open Lovable (github.com/mendableai)
177 points by iamflimflam1 10 months ago | 55 comments
26.
My Lethal Trifecta talk at the Bay Area AI Security Meetup (simonwillison.net)
430 points by vismit2000 10 months ago | 115 comments
27.
Developing with Kiro: Amazon's New Agentic IDE (yehudacohen.substack.com)
93 points by cebert 10 months ago | 86 comments
28.
Qwen3-235B-A22B-Thinking-2507 (huggingface.co)
155 points by tosh 10 months ago | 64 comments
29.
AccountingBench: Evaluating LLMs on real long-horizon business tasks (penrose.com)
534 points by rickcarlino 10 months ago | 149 comments
30.
Don't bother parsing: Just use images for RAG (morphik.ai)
328 points by Adityav369 10 months ago | 72 comments

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